Hoppe, Adam

• Ph.D., Biophysics, University of Michigan, Ann Arbor

•  M.S., Medical Physics, University of Wisconsin, Madison 

• B.A., Physics & Mathematics, Concordia College, Moorhead, Minn.

The biological focus of my lab is to explain how the motility and inflammatory functions of macrophages are controlled by spatially-encoded biochemistries downstream of the macrophage colony stimulating factor receptor (mCSFR). mCSFR signaling is known to control the accumulation of macrophages in tissues where they mediate innate immune responses or aid in disease progression of atherosclerosis and cancer. By applying our quantitative techniques to this problem, these studies should provide new insights into the mechanisms of organized receptor signaling while potentially identifying novel pharmacological targets for controlling macrophage behavior and treatment of human diseases.