Tippabattini, Jayaramudu

The research interest in our lab is helping to save people from Bacterial Infections by developing polymer-based hydrogels that help to protect wounds from bacterial attack. The skin, serving as a physical and chemical barrier, is the most frequently injured organ in the human body, making it susceptible to infections. Therefore, effective protection is critical during wound healing. The long-term goal of this project is to prepare non-toxic, biocompatible substances that promote healing while offering antibacterial protection. The hydrogels we develop play an important role in wound care, as they provide several benefits, including maintaining a moist environment around the wound, easy application of irregularly shaped wounds, pathogen resistance, ease of application and removal, oxygen permeability, and adaptability. These materials help maintain a moist environment at the wound site, which not only prevents bacterial infections but also accelerates the healing process by releasing therapeutic agents in a controlled manner.

The specific aims are:

·         Design and Synthesis of Injectable Bioactive Hydrogels.

·         Characterization of Hydrogel Properties: Rheological and Physicochemical Analysis.

·         Engineering Stimuli-Responsive Hydrogel Networks for Controlled Drug Release.

·         Analysis of Antibacterial Activity and Biofilm Inhibition.

·         Assess the Cytocompatibility and Biocompatibility.