Tippabattini, Jayaramudu

The research interest in our lab is to help prevent bacterial infections by developing polymer-based hydrogels that protect wounds from bacterial attack. The skin, serving as a physical and chemical barrier, is the most frequently injured organ in the human body, making it susceptible to infections. Therefore, effective protection is critical during wound healing. The goal of this project is to create a non-toxic, non invasive, biocompatible materials that promote healing while providing antibacterial protection. The electrospun membranes we develop play an important role in wound care, as they provide several benefits, including maintaining a moist environment around the wound, easy application to resist the pathogen, ease of application and removal, oxygen permeability, and adaptability.  These materials help maintain a moist environment at the wound site, which not only prevents bacterial infections but also accelerates the healing process by releasing therapeutic agents in a controlled manner.

The specific aims are:

·         Development of engineered 

·         Characterization of Hydrogel Properties: Rheological and Physicochemical Analysis.

·         Engineering Stimuli-Responsive Hydrogel Networks for Controlled Drug Release.

·         Analysis of Antibacterial Activity and Biofilm Inhibition.

·         Assess the Cytocompatibility and Biocompatibility.